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Study reverses thinking on genetic links to stress, depression

In fact, a recent study published in  PLOS One  indicates that only about half of scientific discoveries will be replicated and stand the test of time. So perhaps it shouldn't come as a surprise that new research led by Washington University School of Medicine in St. Louis shows that an influential 2003 study about the interaction of genes, environment and depression may have missed the mark. Since its publication in Science, that original paper has been cited by other researchers more than 4,000 times, and some 100 other studies have been published about links between a serotonin-related gene, stressful life events and depression risk. It indicated that people with a particular variant of the serotonin transporter gene were not as well-equipped to deal with stressful life events and, when encountering significant stress, were mor e likely to develop depression. Such conclusions were widely accepted, mainly because antidepressant drugs called selective serotonin reuptak...

Less fear: How LSD affects the brain

Hallucinogens have many different effects on the psyche; among other things, they alter perception, thought, and temporal and emotional experience. After the Basel-based chemist Albert Hofmann discovered lysergic acid diethylamide (LSD) in the 1940s, there was a huge amount of interest in the substance, particularly in psychiatry. It was hoped, for example, that it could provide insights into the development of hallucinations, and studies were conducted on its effectiveness on illnesses such as depression or alcohol dependency. In the 1960s, LSD was declared illegal worldwide, and medical research on it came to a standstill. In the last few years, however, interest in researching hallucinogens for medical purposes has been revived. Psychoactive substances such as LSD, particularly in combination with psychotherapies, could offer an alternative to conventional medication. It is now known that hallucinogens bind to a receptor of the neurotransmitter serotonin; how the changes of cons...

Using Instagram can increase adolescents' closeness to friends

Eline Frison (University of Leuven) will present her findings at the 67th Annual Conference of the International Communication Association in San Diego, CA. From 2013-2014, Frison set up a large-scale longitudinal panel study to investigate the relationships between Flemish adolescents' social networking site use and their well-being. Students filled out paper-and-pencil surveys between 6 month periods. The surveys asked students about their use of social networking sites like Facebook, Snapchat, and Instagram, and their well-being (depressive symptoms, life satisfaction, loneliness). The data analyzed revealed that frequent use of Instagram at one point was related to greater depression six months later. However, using Instagram at one point was also related to increased closeness to friends (perception that they are appreciated and loved by their friends) six months later, which in turn was related to lower levels of depression. Various researchers have investigated the imp...